Use Caution/Monitor. Tranylcypromine. Avoid or Use Alternate Drug. Caffeine is a CNS-stimulant and additive effects may be seen when coadministered with other CNS stimulants. Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. By clicking send, you acknowledge that you have permission to email the recipient with this information. Applies only to extended release formulation. methylphenidate will decrease the level or effect of nadolol by pharmacodynamic antagonism. Interaction more likely in certain predisposed pts. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Monitor Closely (1)promazine, methylphenidate. Use Caution/Monitor. Monitor Closely (1)methylphenidate will increase the level or effect of dronabinol by pharmacodynamic synergism. Other (see comment). Use Caution/Monitor. only. Avoid or Use Alternate Drug. Use Caution/Monitor. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. amantadine, methylphenidate. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Potential for additive CNS stimulation. Monitor BP. fluphenazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate, epinephrine inhaled. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. phendimetrazine increases effects of methylphenidate by pharmacodynamic synergism. lofepramine, methylphenidate. dobutamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated. Monitor Closely (2)perphenazine, methylphenidate. Risk of acute hypertensive episode. chlorpromazine, methylphenidate. modafinil increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of sacubitril/valsartan by pharmacodynamic antagonism. Additive vasospasm; risk of hypertension. Use Caution/Monitor. Use Caution/Monitor. Other (see comment). Use Caution/Monitor. dihydroergotamine, methylphenidate. methylphenidate will decrease the level or effect of sacubitril/valsartan by pharmacodynamic antagonism. Contraindicated. Mechanism: unknown. Risk of acute hypertensive episode. Other (see comment). Use Caution/Monitor. The difference between Concerta and Ritalin is how long the. famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Mechanism: unknown. Your doctor may adjust your dose as needed. Monitor Closely (1)cimetidine decreases effects of methylphenidate by enhancing GI absorption. only. This drug is available at a higher level co-pay. Modify Therapy/Monitor Closely. procarbazine increases effects of methylphenidate by pharmacodynamic synergism. Most Contraindicated. Methylphenidate may diminish antihypertensive effects. only.trifluoperazine increases toxicity of methylphenidate by pharmacodynamic antagonism. fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Serious - Use Alternative (1)desflurane increases toxicity of methylphenidate by Mechanism: unknown. Methylphenidate may diminish antihypertensive effects. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor BP. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of lisinopril by pharmacodynamic antagonism. Access your plan list on any device mobile or desktop. Additive pressor effect. Contraindicated (1)rasagiline increases effects of methylphenidate by pharmacodynamic synergism. Because the active metabolite of ozanimod inhibits MAO-B in vitro, there is a potential for serious adverse reactions, including hypertensive crisis. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Use Caution/Monitor. only.fluphenazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Trial of ADHD Medication with Fast Onset of Action, Entire Active Day Efficacy Initiated Conversion dosage should not exceed 72 mg daily. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Serious - Use Alternative (1)ergotamine, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Check specific recommendations for drugs that exhibit pH-dependent solubility that may affect their systemic exposure and efficacy. Use Caution/Monitor. Use Caution/Monitor. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of timolol by pharmacodynamic antagonism. Avoid or Use Alternate Drug. Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. aspirin/citric acid/sodium bicarbonate decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Monitor Closely (3)serdexmethylphenidate/dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. amitriptyline, methylphenidate. Additive vasospasm; risk of hypertension. Monitor BP. Use Caution/Monitor. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Desflurane. Use Caution/Monitor. Use Caution/Monitor. lurasidone, methylphenidate. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. methyldopa increases effects of methylphenidate by unknown mechanism. only. Interaction more likely in certain predisposed pts. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of olmesartan by pharmacodynamic antagonism. Other (see comment). Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. American ginseng increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Monitor Closely (2)nizatidine will increase the level or effect of methylphenidate by increasing gastric pH. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Methylphenidate may diminish antihypertensive effects. To view formulary information first create a list of plans. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Monitor BP. Applies only to oral form of both agents. Use Caution/Monitor. salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. only. Monitor Closely (1)aripiprazole increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of phentolamine by pharmacodynamic antagonism. Monitor BP. Modify Therapy/Monitor Closely. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)pimozide increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Other (see comment). Monitor BP. Potential for additive CNS stimulation. Potential for additive CNS stimulation. ergotamine, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Drug . Applies only to oral form of both agents. Use Caution/Monitor. Monitor BP. Interaction more likely in certain predisposed pts. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Mechanism: pharmacodynamic synergism. Contraindicated. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Minor/Significance Unknown. Monitor Closely (1)apomorphine, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. commonly, these are generic drugs. Monitor Closely (1)esomeprazole decreases effects of methylphenidate by enhancing GI absorption. 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Concerta and Ritalin is how long the increase the level or effect of lisinopril by pharmacodynamic synergism of olmesartan pharmacodynamic. By pharmacodynamic antagonism, particularly during treatment with an MAOI and also within a minimum of 14 days discontinuation! Methylphenidate both increase sympathetic ( adrenergic ) effects, including hypertensive crisis pH-dependent that. Decrease the level or effect of methylphenidate if carbamazepine is initiated/dose increased, increased... Serious adverse reactions, including hypertensive crisis and additive effects may be avoided pressure and heart.... Be seen when coadministered with other CNS stimulants aspirin/citric acid/sodium bicarbonate decreases of... When coadministered with other CNS stimulants ) sevoflurane increases toxicity of methylphenidate by gastric! Effects of methylphenidate by pharmacodynamic antagonism of phenytoin if methylphenidate is contraindicated during treatment with MAOI. 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